Article
Efficacy of immune checkpoint inhibitors in non-small cell lung cancer with NTRK family mutations.
BMC pulmonary medicine - 29 Nov 2023
Shang Xiaoling, Zhang Wengang, Han Wenfei, Xia Handai, Liu Ni, Wang Xiuwen, Liu Yanguo
Abstract excerpt
BACKGROUND: The efficacy of immune checkpoint inhibitors (ICIs) in non-small cell lung cancer (NSCLC) patients harboring neurotrophin receptor kinase (NTRK) family mutations remains obscure. METHODS: The Zehir cohort from cBioPortal was used to analyze the mutations (MT) frequency of NTRK family in patients with NSCLC, and their correlation with clinical characteristics and patient survival. The influence of NTRK...
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