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Osimertinib as first-line treatment for elderly patients with advanced EGFR mutation-positive non-small cell lung cancer in a real-world setting (OSI-FACT-EP).

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2023

Sakata Yoshihiko, Saito Go, Sakata Shinya, Oya Yuko, Tamiya Motohiro, Suzuki Hidekazu, Shibaki Ryota, Okada Asuka, Yokoyama Toshihide, Matsumoto Hirotaka, Otsuki Taiichiro, Sato Yuki, Junji Uchida, Tsukita Yoko, Inaba Megumi, Ikeda Hideki, Arai Daisuke, Maruyama Hirotaka, Hara Satoshi, Tsumura Shinsuke, Morinaga Jun, Sakagami Takuro

Abstract excerpt

OBJECTIVES: Osimertinib is the primary treatment for patients with epidermal growth factor receptor (EGFR) mutation-positive advanced non-small cell lung cancer. However, evidence of the outcomes of osimertinib treatment in patients over 75 years of age in the real-world setting is limited. MATERIALS AND METHODS: This retrospective study analyzed the data of 538 patients (203 elderly and 335 non-elderly) with...

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PMID: 37992594
DOI: 10.1016/j.lungcan.2023.107426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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