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Article

Spastic Paraplegia Type 7-Associated Optic Neuropathy: A Case Series.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society - 1 Dec 2024

Bell Carter A, Ko Melissa W, Mackay Devin D, Bursztyn Lulu L C D, Grossman Scott N

Abstract excerpt

BACKGROUND: Hereditary optic neuropathies comprise a group of clinically and genetically heterogeneous disorders. Optic neuropathy has been previously reported in families with spastic paraplegia type 7 ( SPG7) gene mutations. However, the typical time course and clinical presentation of SPG7 -associated optic neuropathy is poorly understood. We report a series of 5 patients harboring pathogenic SPG7 mutations...

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Identifiers

PMID: 37983191
DOI: 10.1097/WNO.0000000000002039

Genes

SPG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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