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Network pharmacology and molecular docking reveal potential mechanism of esculetin in the treatment of ulcerative colitis

10 Nov 2023

Abstract excerpt

Ulcerative colitis (UC) is a chronic inflammatory bowel disease of the colonic mucosa. Esculetin is a type of natural coumarin that has many pharmacological activities such as antioxidant, anticancer, anti-inflammatory, etc. A previous study showed that esculetin improved intestinal inflammation and reduced serum proinflammatory cytokines in UC. The present study aimed to utilize network pharmacology and...

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PMID: 37960728
DOI: 10.1097/md.0000000000035852

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