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Endothelial heterogeneity and their relevance in cardiac development and coronary artery disease

6 Nov 2023

Abstract excerpt

Micro- and macrovascular endothelial cells (ECs) are characterized by structural and functional heterogeneity, which is also reflected in their secretory activity. The root of this heterogeneity and related regulatory mechanisms are still poorly understood. During embryogenesis, microvascular ECs participate in organogenesis prior to the development of the fetal circulation, suggesting that ECs are capable of...

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PMID: 37940065
DOI: 10.1016/j.vph.2023.107242

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