Article
The impact of oncogenic driver mutations on neoadjuvant immunotherapy outcomes in patients with resectable non-small cell lung cancer.
Cancer immunology, immunotherapy : CII - 1 Dec 2023
Shen Ziyun, Teng Meixin, Han Lu, Bian Dongliang, Zhang Jing, Zhu Xinsheng, Qing Yang, Hu Shiqi, Chen Yan, Yao Wangchao, Yu Huansha, Zhang Lele, Zhang Peng
Abstract excerpt
BACKGROUND: Neoadjuvant immunotherapy has been demonstrated to be effective and safe in resectable non-small cell lung cancer (NSCLC) patients. However, the presence of different oncogenic driver mutations may affect the tumor microenvironment and consequently influence the clinical benefit from immunotherapy. METHODS: This retrospective study included consecutive NSCLC patients (stage IIA to IIIB) who underwent...
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