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Suppression of the dwarf phenotype of an Arabidopsis mutant defective in thermospermine biosynthesis by a synonymous codon change in the SAC51 uORF.

Molecular genetics and genomics : MGG - 1 Nov 2023

Nishii Yuichi, Koyama Daiki, Fukushima Hiroko, Takahashi Taku

Abstract excerpt

Thermospermine plays a critical role in negatively regulating xylem development in angiosperms. A mutant of Arabidopsis thaliana that is defective in thermospermine biosynthesis, acaulis5 (acl5), exhibits a dwarf phenotype with excessive xylem formation. Mechanistically thermospermine acts in attenuating the inhibitory effect of an evolutionarily conserved upstream open reading frame (uORF) on the main ORF of...

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PMID: 37845372
DOI: 10.1007/s00438-023-02076-4

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Suppression of the dwarf phenotype of an Arabidopsis mutant defective in thermospermine biosynthesis by a synonymous codon change in the SAC51 uORF.PMID 37845372Read ↗

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