Article
Effect of single nucleotide polymorphisms on the structure of long noncoding RNAs and their interaction with RNA binding proteins.
Bio Systems - 1 Nov 2023
Singh Mandakini, Kumar Santosh
Abstract excerpt
Long non-coding RNAs (lncRNA) are emerging as a new class of regulatory RNAs with remarkable potential to be utilized as therapeutic targets against many human diseases. Several genome-wide association studies (GWAS) have catalogued Single Nucleotide Polymorphisms (SNPs) present in the noncoding regions of the genome from where lncRNAs originate. In this study, we have selected 67 lncRNAs with GWAS-tagged SNPs...
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