Article
Integration of eQTL and machine learning to dissect causal genes with pleiotropic effects in genetic regulation networks of seed cotton yield.
Cell reports - 26 Sept 2023
Zhao Ting, Wu Hongyu, Wang Xutong, Zhao Yongyan, Wang Luyao, Pan Jiaying, Mei Huan, Han Jin, Wang Siyuan, Lu Kening, Li Menglin, Gao Mengtao, Cao Zeyi, Zhang Hailin, Wan Ke, Li Jie, Fang Lei, Zhang Tianzhen, Guan Xueying
Abstract excerpt
The dissection of a gene regulatory network (GRN) that complements the genome-wide association study (GWAS) locus and the crosstalk underlying multiple agronomical traits remains a major challenge. In this study, we generate 558 transcriptional profiles of lint-bearing ovules at one day post-anthesis from a selective core cotton germplasm, from which 12,207 expression quantitative trait loci (eQTLs) are...
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