Article
Hereditary myotonia in cats associated with a new homozygous missense variant p.Ala331Pro in the muscle chloride channel ClC-1.
Journal of veterinary internal medicine - 1 Jan 2000
Corrêa Sílvia, Basso Roberta Martins, Cerri Fabricio Moreira, de Oliveira-Filho José Paes, Araújo João Pessoa, Torelli Sandra Regina, Salán Livia Pinheiro Chagas da Cunha, Salán Maurício Oliveira, Macedo Isabella Zeque, Borges Alexandre Secorun
Abstract excerpt
Three-related cats were evaluated for a history of short-strided gait and temporary recumbency after startle. Neurological examination, electromyography (EMG), muscle biopsies, and a chloride voltage-gated channel 1 (CLCN1) molecular study were performed. Clinically, all 3 cats presented myotonia with warm-up phenomenon and myotonic discharges during EMG examination. Muscle biopsies showed normal muscle...
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