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Gut microbial carbohydrate metabolism contributes to insulin resistance

30 Aug 2023

Abstract excerpt

Abstract Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2 diabetes 1,2 . Previous metagenomic studies have described the characteristics of gut microbiota and their roles in metabolizing major nutrients in insulin resistance 3–9 . In particular, carbohydrate metabolism of commensals has been proposed to contribute up to 10% of the host’s overall energy extraction 10 ,...

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PMID: 37648852
DOI: 10.1038/s41586-023-06466-x

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