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Article

DYT-TOR1A dystonia: an update on pathogenesis and treatment

10 Aug 2023

Abstract excerpt

DYT- TOR1A dystonia is a neurological disorder characterized by involuntary muscle contractions and abnormal movements. It is a severe genetic form of dystonia caused by mutations in the TOR1A gene. TorsinA is a member of the AAA + family of adenosine triphosphatases (ATPases) involved in a variety of cellular functions, including protein folding, lipid metabolism, cytoskeletal organization, and...

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PMID: 37638318
DOI: 10.3389/fnins.2023.1216929

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