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The Genetic Determinants of Axial Length: From Microphthalmia to High Myopia in Childhood

25 Aug 2023

Abstract excerpt

The axial length of the eye is critical for normal visual function by enabling light to precisely focus on the retina. The mean axial length of the adult human eye is 23.5 mm, but the molecular mechanisms regulating ocular axial length remain poorly understood. Underdevelopment can lead to microphthalmia (defined as a small eye with an axial length of less than 19 mm at 1 year of age or less than 21 mm in...

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PMID: 37624667
DOI: 10.1146/annurev-genom-102722-090617

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