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25-hydroxyvitamin D sufficiency is associated with lower de novo anti-HLA donor specific antibody and better kidney transplant outcomes.

HLA - 1 Jan 2024

Bakis Hugo, Bouthemy Charlène, Corcuff Jean-Benoît, Lauro Cindy, Guidicelli Gwendaline, Cargou Marine, Guibet Claire, Taton Benjamin, Merville Pierre, Couzi Lionel, Moreau Karine, Visentin Jonathan

Abstract excerpt

T-cell mediated rejection (TCMR), de novo anti-HLA donor-specific antibodies (dnDSAs) and ensuing antibody-mediated rejection (ABMR) reduce kidney transplantation (KT) survival. The immunomodulatory effects of 25-hydroxyvitamin D [25(OH)D] could be beneficial for KT outcomes. We aimed to evaluating the association between 25(OH)D levels, the development of dnDSAs, clinical TCMR and ABMR, and graft survival. This...

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PMID: 37604171
DOI: 10.1111/tan.15187

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