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Identification of vaccine candidates against rhodococcus equi by combining pangenome analysis with a reverse vaccinology approach

25 Jul 2023

Abstract excerpt

Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that can cause life-threatening infections. The rapid evolution of multidrug-resistant R. equi and the fact that there is no currently licensed effective vaccine against R. equi warrant the need for vaccine development. Reverse vaccinology (RV), which involves screening a pathogen's entire genome and proteome using various web-based prediction tools,...

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PMID: 37576287
DOI: 10.1016/j.heliyon.2023.e18623

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