Non-Invasive Prenatal Testing (NIPT): Reliability, Challenges, and Future Directions

Abstract excerpt

Non-invasive prenatal testing was first discovered in 1988; it was primarily thought to be able to detect common aneuploidies, such as Patau syndrome (T13), Edward Syndrome (T18), and Down syndrome (T21). It comprises a simple technique involving the analysis of cell-free foetal DNA (cffDNA) obtained through maternal serum, using advances in next-generation sequencing. NIPT has shown promise as a simple and...

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• Fetal and Pediatric Neurological Disorders
• Genomic variations and chromosomal abnormalities
• Prenatal Screening and Diagnostics