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BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides

5 Aug 2023

Abstract excerpt

Abstract Vitamin B12 (cobalamin) is required for most human gut microbes, many of which are dependent on scavenging to obtain this vitamin. Since bacterial densities in the gut are extremely high, competition for this keystone micronutrient is severe. Contrasting with Enterobacteria, members of the dominant genus Bacteroides often encode several BtuB vitamin B12 outer membrane transporters together with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37543597
DOI: 10.1038/s41467-023-40427-2

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