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Article

A novel mutation in PCD-associated gene DNAAF3 causes male infertility due to asthenozoospermia.

Journal of cellular and molecular medicine - 1 Oct 2023

Wan Feng, Yu Lan, Qu Xiaowei, Xia Yanqing, Feng Ke, Zhang Lei, Zhang Na, Zhao Guihua, Zhang Cuilian, Guo Haibin

Abstract excerpt

Primary ciliary dyskinesia (PCD) is a rare autosomal-recessive disease manifested with recurrent infections of respiratory tract and infertility. DNAAF3 is identified as a novel gene associated with PCD and different mutations in DNAAF3 results in different clinical features of PCD patients, such as situs inversus, sinusitis and bronchiectasis. However, the sperm phenotypic characteristics of PCD males are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37537752
DOI: 10.1111/jcmm.17881
PMCID: PMC10568663

Genes

DNAAF3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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A novel mutation in PCD-associated gene DNAAF3 causes male infertility due to asthenozoospermia.PMID 37537752Read ↗

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