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Article

Apolipoprotein E ε2 allele is associated with lower risk of carotid artery obstruction in a population-based autopsy study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Sept 2023

Paradela Regina Silva, Farias-Itao Daniela Souza, Leite Renata E P, Pasqualucci Carlos A, Grinberg Lea T, Naslavsky Michel Satya, Zatz Mayana, Nitrini Ricardo, Jacob-Filho Wilson, Suemoto Claudia Kimie

Abstract excerpt

INTRODUCTION: Apolipoprotein E (APOE) ε4 allele has been associated with higher carotid atherosclerosis risk, while the APOE-ε2 seems to decrease this risk. Data from autopsy studies, where carotid arteries can be evaluated in their full extension, is scarce. Therefore, we investigated the association between APOE alleles and direct morphometric measurements of carotid atherosclerosis in an autopsy study with an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37531722
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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