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Prognostic Impact of Central Nervous System Recurrence After Surgery in Patients With Epidermal Growth Factor Receptor Mutation-positive Non-small-cell Lung Cancer.

Anticancer research - 1 Aug 2023

Okamoto Tatsuro, Takenaka Tomoyoshi, Yamazaki Koji, Hamatake Motoharu, Miura Naoko, Takenoyama Mitsuhiro, Kometani Takuro, Ueda Hitoshi, Kouso Hidenori, Yano Tokujiro

Abstract excerpt

BACKGROUND/AIM: Adjuvant therapy using third-generation tyrosine kinase inhibitors (TKI) demonstrated improved central nervous system (CNS) disease-free survival after surgery in patients with epidermal growth factor receptor (EGFR) mutation-positive lung cancer. However, the prognostic impact of CNS recurrence in surgical patients remains unknown. We evaluated the effect of CNS recurrence on post-recurrence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37500139
DOI: 10.21873/anticanres.16532

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