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Article

MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis

25 Jul 2023

Abstract excerpt

An emerging but less explored shared pathophysiology across microbiota-gut-brain axis disorders is aberrant miRNA expression, which may represent novel therapeutic targets. miRNAs are small, endogenous non-coding RNAs that are important transcriptional repressors of gene expression. Most importantly, they regulate the integrity of the intestinal epithelial and blood-brain barriers and serve as an important...

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PMID: 37499702
DOI: 10.1016/j.phrs.2023.106870

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