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Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection

19 Jul 2023

Abstract excerpt

Approximately 10% of individuals diagnosed with Clostridium difficile infection (CDI) show the resistance to fecal microbiota transplantation (FMT), with the underlying mechanisms remaining elusive. Deciphering the intricate microbiome profile within this particular subset of FMT-refractory patients via clinical FMT investigations assumes paramount importance, as it holds the key to designing targeted therapeutic...

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PMID: 37469017
DOI: 10.1080/19490976.2023.2236362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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