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Article

Activation Ratio Correlates with IQ in Female Carriers of the FMR1 Premutation.

Cells - 24 Jun 2023

Protic Dragana, Polli Roberta, Hwang Ye Hyun, Mendoza Guadalupe, Hagerman Randi, Durbin-Johnson Blythe, Hayward Bruce E, Usdin Karen, Murgia Alessandra, Tassone Flora

Abstract excerpt

Carriers of the FMR1 premutation (PM) allele are at risk of one or more clinical conditions referred to as FX premutation-associated conditions (FXPAC). Since the FMR1 gene is on the X chromosome, the activation ratio (AR) may impact the risk, age of onset, progression, and severity of these conditions. The aim of this study was to evaluate the reliability of AR measured using different approaches and to...

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Identifiers

PMID: 37443745
DOI: 10.3390/cells12131711
PMCID: PMC10341054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activation Ratio Correlates with IQ in Female Carriers of the FMR1 Premutation.PMID 37443745Read ↗

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