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Article

Optimization of Capillary-Based Western Blotting for MYO7A.

Advances in experimental medicine and biology - 1 Jan 2023

Calabro Kaitlyn R, Boye Sanford L, Boye Shannon E

Abstract excerpt

Myosin VIIA (MYO7A)-associated Usher syndrome type 1B (USH1B) is a severe disorder that impacts the auditory, vestibular, and visual systems of affected patients. Due to the large size (~7.5 kb) of the MYO7A coding sequence, we have designed a dual adeno-associated virus (AAV) vector-based approach for the treatment of USH1B-related vision loss. Due to the added complexity of dual-AAV gene therapy, careful...

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Identifiers

PMID: 37440024
DOI: 10.1007/978-3-031-27681-1_19

Genes

MYO7A

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PubMed metadata and Literature Corpus relationships.

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Detection of Dystrophin Dp71 in Human Skeletal Muscle Using an Automated Capillary Western Assay SystemSemantic proximity Read ↗

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