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The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization

28 Jun 2023

Abstract excerpt

STUDY QUESTION: What clinical and laboratory differences emerge from parallel direct comparison of embryos reaching the blastocyst stage between Days 4, 5, 6, and 7 (Days 4-7)? SUMMARY ANSWER: Increasing times to blastocyst formation are associated with a worse clinical outcome and perturbations in developmental patterns appear as early as the fertilization stage. WHAT IS KNOWN ALREADY: Previous evidence...

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PMID: 37381073
DOI: 10.1093/humrep/dead136

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