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Article

Reassortment and genomic analysis of a G9P[8]-E2 rotavirus isolated in China.

Virology journal - 22 Jun 2023

Peng Rui, Li Dandi, Wang Jindong, Xiong Guangping, Wang Mengxuan, Liu Dan, Wei Yuhang, Pang Lili, Sun Xiaoman, Li Huiying, Kong Xiangyu, Shahar Saleha, Duan Zhaojun

Abstract excerpt

OBJECTIVE: To isolate a prevalent G9P[8] group A rotavirus (RVA) (N4006) in China and investigate its genomic and evolutionary characteristics, with the goal of facilitating the development of a new rotavirus vaccine. METHODS: The RVA G9P[8] genotype from a diarrhea sample was passaged in MA104 cells. The virus was evaluated by TEM, polyacrylamide gel electrophoresis, and indirect immunofluorescence assay. The...

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Identifiers

PMID: 37349792
DOI: 10.1186/s12985-023-02064-5
PMCID: PMC10286334

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