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Pandemic potential of poxviruses: From an ancient killer causing smallpox to the surge of monkeypox

19 Jun 2023

Abstract excerpt

Smallpox caused by the variola virus (VARV) was one of the greatest infectious killers of mankind. Historical records trace back smallpox for at least a millennium while phylogenetic analysis dated the ancestor of VARV circulating in the 20th century into the 19th century. The discrepancy was solved by the detection of distinct VARV sequences first in 17th-century mummies and then in human skeletons dated to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37335284
DOI: 10.1111/1751-7915.14294

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