Article
POTEE mutation as a potential predictive biomarker for immune checkpoint inhibitors in lung adenocarcinoma.
Investigational new drugs - 1 Aug 2023
Li Yongzhao, Yang Qidong, Liu Yaqin, Yi Huan, Ju Yongzhi, Qi Guoyan
Abstract excerpt
Precise selection of patients who could benefit from immune checkpoint inhibitors (ICIs) is an important challenge for immunotherapy in lung cancer. POTEE (POTE Ankyrin Domain Family Member E) is a member of one primate-specific gene family which have been identified as cancer-related antigens and potential target for immunotherapy of cancer. Here, we investigated the correlation between POTEE mutation and the...
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