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Article

Mutations in the CYP27B1 gene cause vitamin D dependent rickets in pugs.

Journal of veterinary internal medicine - 1 Jan 2000

Rohdin Cecilia, Wang Chao, Brander Gustaf, Rondahl Veronica, Karlsson Åsa, Friling Lisa, Fischetti Anthony, Meadows Jennifer, Häggström Jens, Jäderlund Karin Hultin, Ljungvall Ingrid, Lindblad-Toh Kerstin

Abstract excerpt

Rickets is a disorder of bone development and can be the result of either dietary or genetic causes. Here, related pugs from 2 litters were included. Three pugs had clinical signs including, lameness, bone deformities, and dyspnea. One other pug was found dead. Radiographs of 2 affected pugs, 5 and 6 months old, showed generalized widening, and irregular margination of the physes of both the appendicular and the...

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37293695
DOI: 10.1111/jvim.16791
PMCID: PMC10365047

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Mutations in the CYP27B1 gene cause vitamin D dependent rickets in pugs.PMID 37293695Read ↗

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