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The role of protein phosphatase 2A (PP2A) in the unfolded protein response (UPR) of plants.

Biochemical and biophysical research communications - 30 Aug 2023

Ko Ki Seong, Yoo Jae Yong, Vu Bich Ngoc, Lee Young Eun, Choi Ha Na, Lee Yoo Na, Fanata Wahyu Indra Duwi, Harmoko Rikno, Chung Woo Sik, Hong Jong Chan, Lee Kyun Oh

Abstract excerpt

Protein phosphatase 2A (PP2A) is a key regulator of plant growth and development, but its role in the endoplasmic reticulum (ER) stress response remains elusive. In this study, we investigated the function of PP2A under ER stress using loss-of-function mutants of ROOTS CURL of NAPHTHYLPHTHALAMIC ACID1 (RCN1), a regulatory A1 subunit isoform of Arabidopsis PP2A. RCN1 mutants (rcn1-1 and rcn1-2) exhibited reduced...

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PMID: 37290287
DOI: 10.1016/j.bbrc.2023.05.106

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