Article
Analysis of KLF7 and KLF5 transcription factors gene variants in coronary artery disease.
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 1 Oct 2023
Akbari Kordkheyli Vahid, Poursheikhani Arash, Sharobandi Seyed Hasan, Hosseini Sayed Mostafa
Abstract excerpt
INTRODUCTION AND OBJECTIVE: Genetic susceptibility has a key role in the pathogenesis of coronary artery disease (CAD). KLF5 and KLF7 are transcriptional factors essential to cell development and differentiation. Their genetic variants have been associated with the risk of metabolic disorders. The present study aimed to evaluate the possible correlation of KLF5 (rs3812852) and KLF7 (rs2302870) single nucleotide...
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