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Article

Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2.

BMC molecular and cell biology - 26 May 2023

Bieder Andrea, Chandrasekar Gayathri, Wason Arpit, Erkelenz Steffen, Gopalakrishnan Jay, Kere Juha, Tapia-Páez Isabel

Abstract excerpt

BACKGROUND: DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both have demonstrated roles in neuronal migration, in cilia growth and function and they both are cytoskeletal interactors. In addition, they both have been characterized as ciliopathy genes. However, their exact molecular functions are still incompletely described. Based on these known roles,...

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PMID: 37237337
DOI: 10.1186/s12860-023-00483-4
PMCID: PMC10224228

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