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Article

Multi-omics integration analysis of GPCRs in pan-cancer to uncover inter-omics relationships and potential driver genes.

Computers in biology and medicine - 1 Jul 2023

Li Shiqi, Chen Xin, Chen Jianfang, Wu Binjian, Liu Jing, Guo Yanzhi, Li Menglong, Pu Xuemei

Abstract excerpt

G protein-coupled receptors (GPCRs) are the largest drug target family. Unfortunately, applications of GPCRs in cancer therapy are scarce due to very limited knowledge regarding their correlations with cancers. Multi-omics data enables systematic investigations of GPCRs, yet their effective integration remains a challenge due to the complexity of the data. Here, we adopt two types of integration strategies,...

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Identifiers

PMID: 37201441
DOI: 10.1016/j.compbiomed.2023.106988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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