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Gut microbiome combined with metabolomics reveals biomarkers and pathways in central precocious puberty

11 May 2023

Abstract excerpt

BACKGROUND: Central precocious puberty (CPP) is a common disease in prepubertal children and results mainly from disorders in the endocrine system. Emerging evidence has highlighted the involvement of gut microbes in hormone secretion, but their roles and downstream metabolic pathways in CPP remain unknown. METHODS: To explore the gut microbes and metabolism alterations in CPP, we performed the 16S rRNA...

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PMID: 37170084
DOI: 10.1186/s12967-023-04169-5

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