Article
Confirmatory DPYD Testing in Patients Receiving Fluoropyrimidines Who are Suspected DPYD Variant Carriers Based on a Genetic Data Repository.
Clinical pharmacology and therapeutics - 1 Aug 2023
Pasternak Amy L, Seda Robinson, Lipa Joseph, McDevitt Rachel L, Crysler Oxana V, Swiecicki Paul L, Schneider Bryan J, Vanderwerff Brett, Henry N Lynn, Krauss John C, Sahai Vaibhav, Hertz Daniel L
Abstract excerpt
Using pharmacogenetics (PGx) to inform clinical decision making can benefit patients but clinical use of PGx testing has been limited. Existing genetics data obtained in the course of research could be used to identify patients who are suspected, but have not yet been confirmed, to carry clinically actionable genotypes, in whom confirmatory genetic testing could be conducted for highly efficient PGx...
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