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Article

Anatomical and functional maturation of the mid-gestation human enteric nervous system

9 May 2023

Abstract excerpt

Immature gastrointestinal motility impedes preterm infant survival. The enteric nervous system controls gastrointestinal motility, yet it is unknown when the human enteric nervous system matures enough to carry out vital functions. Here we demonstrate that the second trimester human fetal enteric nervous system takes on a striped organization akin to the embryonic mouse. Further, we perform ex vivo functional...

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Share to Congenital gastrointestinal and neural anomalies
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PMID: 37160892
DOI: 10.1038/s41467-023-38293-z

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