Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemical Screening for Fetal Trisomy 21: Pathophysiology of Maternal Serum Markers and Involvement of the Placenta

21 Apr 2023

Abstract excerpt

It is now well established that maternal serum markers are often abnormal in fetal trisomy 21. Their determination is recommended for prenatal screening and pregnancy follow-up. However, mechanisms leading to abnormal maternal serum levels of such markers are still debated. Our objective was to help clinicians and scientists unravel the pathophysiology of these markers via a review of the main studies published...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Anomalies and Fetal Surgery
Share to Pregnancy and preeclampsia studies
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37108840
DOI: 10.3390/ijms24087669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biochemical Screening for Fetal Trisomy 21: Pathophysiology of Maternal Serum Markers and Involvement of the PlacentaPMID 37108840Read ↗

Current controversies in prenatal diagnosis 2: for those women screened by NIPT using cell free DNA, maternal serum markers are obsoleteSemantic proximity Read ↗

Review: placental biomarkers for assessing fetal healthSemantic proximity Read ↗

The Update of Fetal Growth Restriction Associated with BiomarkersSemantic proximity Read ↗

Prenatal screening for trisomy 21: recent advances and guidelinesSemantic proximity Read ↗

What is the true fetal loss rate in pregnancies affected by trisomy 21 and how does this influence whether first trimester detection rates are superior to those in the second trimester?Semantic proximity Read ↗

Trisomy 21 in the mid trimester: sonographic phenotyping of the fetus is the key.Semantic proximity Read ↗

Systematic Search for Placental DNA-Methylation Markers on Chromosome 21: Toward a Maternal Plasma-Based Epigenetic Test for Fetal Trisomy 21Semantic proximity Read ↗

Cell-free Fetal DNA — A Trigger for ParturitionSemantic proximity Read ↗

Distinctive pattern of first trimester maternal serum biochemical markers in trisomy 22 pregnanciesSemantic proximity Read ↗

Cell-free fetal DNA versus maternal serum screening for trisomy 21 in pregnant women with and without assisted reproduction technology: a prospective interventional studySemantic proximity Read ↗

Trophoblast Production of a Weakly Bioactive Human Chorionic Gonadotropin in Trisomy 21-Affected PregnancySemantic proximity Read ↗

Trisomy 21 is associated with variable defects in cytotrophoblast differentiation along the invasive pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.