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Article

Short-term culture adaptation of Toxoplasma gondii archetypal II and III field isolates affects cystogenic capabilities and modifies virulence in mice.

International journal for parasitology - 1 Aug 2023

Colos-Arango Alicia, Largo-de la Torre Andrea, Calero-Bernal Rafael, Ortega-Mora Luis-Miguel, Regidor-Cerrillo Javier

Abstract excerpt

Most Toxoplasma gondii research has been carried out using strains maintained in the laboratory for long periods of time. Long-term passage in mice or cell culture influences T. gondii phenotypic traits such as the capability to produce oocysts in cats and virulence in mice. In this work, we investigated the effect of cell culture adaptation in the short term for recently obtained type II (TgShSp1 (Genotype...

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Identifiers

PMID: 37059167
DOI: 10.1016/j.ijpara.2023.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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