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Article

Establishment and validation of a novel anoikis-related prognostic signature of clear cell renal cell carcinoma

28 Mar 2023

Abstract excerpt

Background: Despite progression in its treatment, the clinical outcome of patients with clear cell renal cell carcinoma (ccRCC) remains not ideal. Anoikis is a unique form of programmed apoptosis, owing to insufficient cell-matrix interactions. Anoikis plays a crucial role in tumor migration and invasion, and tumor cells could protect themselves through the capacity of anoikis resistance. Methods: Anoikis-related...

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PMID: 37056778
DOI: 10.3389/fimmu.2023.1171883

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