Article
Genetic and phenotypic heterogeneity of multiple lentigines and precise diagnosis in four Chinese families with multiple lentigines.
Pigment cell & melanoma research - 1 Jan 2000
Guo Kexin, Liu Jia-Wei, Zhang Rui, Wang Rongrong, Ma Dong-Lai, Zhang Xue
Abstract excerpt
Lentigines are well-defined, small, brown macules resulting from the accumulation of melanin content in the basement membrane zone with an increase in the number of melanocytes. Hereditary multiple lentigines (ML) can be associated with multiple genes and are not commonly encountered in clinical practice. Patients can solely have skin involvement or present with multisystemic deformative phenotypes. This study...
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