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Assisted reproductive technologies at the nexus of fertility treatment and disease prevention

13 Apr 2023

Abstract excerpt

Assisted reproductive technology (ART) refers to processing gametes in vitro and usually involves in vitro fertilization. Originally developed for the treatment of infertility, culture of human embryos in vitro also provides an opportunity to screen embryos for inherited genetic disorders of the nuclear and mitochondrial genomes. Progress in identifying causative genetic variants has massively increased the scope...

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PMID: 37053308
DOI: 10.1126/science.adh0073

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