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Article

A Novel RT-LAMP for the Detection of Different Genotypes of Crimean-Congo Haemorrhagic Fever Virus in Patients from Spain.

International journal of molecular sciences - 29 Mar 2023

Febrer-Sendra Begoña, Fernández-Soto Pedro, García-Bernalt Diego Juan, Crego-Vicente Beatriz, Negredo Anabel, Muñor-Bellido Juan Luis, Belhassen-García Moncef, Sánchez-Seco María Paz, Muro Antonio

Abstract excerpt

Crimean-Congo haemorrhagic fever (CCHF) is a potentially lethal tick-borne viral disease with a wide distribution. In Spain, 12 human cases of CCHF have been confirmed, with four deaths. The diagnosis of CCHF is hampered by the nonspecific symptoms, the high genetic diversity of CCHFV, and the biosafety requirements to manage the virus. RT-qPCR and serological tests are used for diagnosis with limitations....

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Identifiers

PMID: 37047384
DOI: 10.3390/ijms24076411
PMCID: PMC10094476

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