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Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles

10 Mar 2023

Abstract excerpt

Aged cells have declined regenerative ability when subjected to environmental insult. Here we elucidate the mechanism by which mechanical stimulus induces hair regeneration at the microenvironmental regulation level using the hair plucking and organoid culture models. We observed that the skin cells harvested from post-plucking day 3 (PPD3) have the best self-organizing ability during skin organoid culture and...

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PMID: 37020681
DOI: 10.1016/j.omtn.2023.03.002

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