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Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants

5 Apr 2023

Abstract excerpt

BACKGROUND: Whether vaccination during pregnancy could reduce the burden of respiratory syncytial virus (RSV)-associated lower respiratory tract illness in newborns and infants is uncertain. METHODS: In this phase 3, double-blind trial conducted in 18 countries, we randomly assigned, in a 1:1 ratio, pregnant women at 24 through 36 weeks' gestation to receive a single intramuscular injection of 120 μg of a...

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PMID: 37018474
DOI: 10.1056/nejmoa2216480

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