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Do pathogens always evolve to be less virulent? The virulence–transmission trade-off in light of the COVID-19 pandemic

31 Mar 2023

Abstract excerpt

The direction the evolution of virulence takes in connection with any pathogen is a long-standing question. Formerly, it was theorized that pathogens should always evolve to be less virulent. As observations were not in line with this theoretical outcome, new theories emerged, chief among them the transmission-virulence trade-off hypotheses, which predicts an intermediate level of virulence as the endpoint of...

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PMID: 37002448
DOI: 10.1007/s42977-023-00159-2

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