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In Vitro Modelling of Oral Microbial Invasion in the Human Colon

27 Mar 2023

Abstract excerpt

model simulating both the physicochemical and microbial (lumen- and mucus-associated microbes) parameters of the human colon (M-ARCOL), a salivary enrichment protocol, and whole-metagenome shotgun sequencing. Our study revealed the importance of integrating the mucus compartment, which retained higher microbial richness during fermentation, showed the preference of oral microbial invaders for the mucosal...

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PMID: 36971547
DOI: 10.1128/spectrum.04344-22

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