Article
Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature
24 Mar 2023
Abstract excerpt
Pediatric neoplasms in the central nervous system (CNS) show extensive clinical and molecular heterogeneity and are fundamentally different from those occurring in adults. Molecular genetic testing contributes to accurate diagnosis and enables an optimal clinical management of affected children. Here, we investigated a rare, molecularly distinct type of pediatric high-grade neuroepithelial tumor (n = 18), that...
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