DeepGeni: deep generalized interpretable autoencoder elucidates gut microbiota for better cancer immunotherapy

Abstract excerpt

Recent studies revealed that gut microbiota modulates the response to cancer immunotherapy and fecal microbiota transplantation has clinical benefits in melanoma patients during treatment. Understanding how microbiota affects individual responses is crucial for precision oncology. However, it is challenging to identify key microbial taxa with limited data as statistical and machine learning models often lose...

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