Article
No association of a Vascular endothelial growth factor A (VEGFA) gene polymorphism with pre-eclampsia among pregnant women in Uganda.
BMC genomics - 20 Mar 2023
Nabweyambo Sheila, Kanyerezi Stephen, Petterson John H-O, Katabazi Fred Ashaba, Ssekagiri Alfred, Mwesigwa Savannah, Mboowa Gerald, Nakazzi Faith, Keesiga Annette, Adroma Moses, Bwanga Freddie, McGovern Naomi, Sande Obondo James, Nakimuli Annettee
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor A (VEGFA) is a major angiogenic factor that plays an important role in the formation of blood vessels during embryonic development. VEGFA has been implicated in the pathophysiology of pre-eclampsia (PE), since pre-eclamptic women present with reduced levels of free circulating VEGFA. The 3' untranslated region (3'-UTR) of the VEGFA gene consists of elements that...
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