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Article

Whole-genome sequencing of Candida haemulonii species complex from Brazil and the United States: Genetic diversity and antifungal susceptibility.

Medical mycology - 3 Apr 2023

de Barros Rodrigues Dality Keffelen, Lockhart Shawn R, Berkow Elizabeth L, Gade Lalitha, Bonfietti Lucas Xavier, Mazo Fávero Gimenes Viviane, Silva Ruiz Luciana, Bronze Macioni Milena, de Souza Carvalho Melhem Marcia

Abstract excerpt

Candida haemulonii complex species can be multidrug-resistant and cause infections such as candidemia. This study determined the genetic relationship between isolates from Brazil and the United States through whole-genome sequencing and performed antifungal susceptibility testing to investigate drug resistance. Contrary to what is widely described, most isolates were susceptible to azoles. However, an atypical...

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PMID: 36931889
DOI: 10.1093/mmy/myad030
PMCID: PMC11321273

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